A6519-D2B1a-1mg Delta-2-avermectin B1a

Description

A6519-D2B1a-1mg Delta-2-avermectin B1a

Delta-2-Avermectin B1a is an irreversible base degradation product of avermectin found in animal treated with avermectin and in the environment. Delta-2-Avermectin B1a is formed by rearrangement of the naturally-occurring delta-3-group to the 2-position. Although less active than the parent, delta-2-avermectin B1a is nonetheless active in the at 1 ppm.

Delta-2-Avermectin B1a is soluble in ethanol, methanol, DMF and DMSO.  

Molecular Formula  : C₄₈H₇₂O₁₄

Molecular Weight : 873.1

Storage Conditions : -20°C

Appearance : White solid

References

Base-catalyzed isomerization of avermectins. Pivnichny J.V. et al. J. Agric. Food Chem. 1988, 36, 826.

Direct determination of avermectins in plasma at nanogram levels by High-Performance Liquid Chromatography. Pivnichny J.V. et al. J. Pharm. Sci. 1980, 72, 1447.